Skip to main content
SMFM 2024 Pregnancy Meeting Main banner
Final Program


Icon Legend
This session is not in your schedule.
This session is in your schedule. Click again to remove it.
Presentation Icons
Additional registration fee required
Additional registration fee required
Faculty have requested this content not be shared on social media
Faculty have requested this content not be shared on social media
CME Credit Offered
CME Credit Offered
Poster Icons
Foundation Awardee
Foundation Awardee
No Social Media
No Social Media
Back
Q&A

Clinical Obstetrics

Poster Session 3

(715) Trends in Tdap and Flu Vaccination in Pregnant People in Relation to the COVID-19 Pandemic

Wednesday, February 14, 2024
8:30 AM – 10:00 AM  
Location: Prince George's Exhibit Hall CDE, Lower Atrium Level
Objective:

We aimed to understand how the COVID-19 pandemic impacted routine Tetanus, Diphtheria, and Pertussis (Tdap) and Influenza (Flu) vaccine administration in pregnancy.


Study Design:

This was a retrospective review of electronic medical records for Tdap and Flu vaccine administration for pregnant patients at a single institution from Mar 2018 to Dec 2022. Patients were assigned to the acute COVID epoch if their gestational age was < 20 weeks by 3/10/2020 and their estimated due date was before 1/1/2021. Pre-COVID and chronic COVID epochs comprised matched months for the two years before and after acute COVID. Bivariate associations between patient characteristics by COVID epoch (Table) and Tdap vaccination (data not shown) were assessed using X2 and ANOVA. Associations between COVID epoch and Tdap vaccination, and COVID epoch and Flu vaccination, were evaluated using multivariable logistic regression. 


Results:

Tdap vaccination rates varied across COVID epoch with a > 10% increase from pre-COVID (75.5%) to acute COVID (85.8%). The Tdap vaccine rate attenuated in the chronic COVID epoch (81.2%). A similar pattern was observed for Flu vaccination with an increasing rate from pre-COVID (48.1%) to acute COVID (53.3%). Flu vaccination rates fell dramatically in the chronic COVID epoch (38.5%) to below pre-COVID levels. Seven covariates were included in regression modeling. Compared to pre-COVID, the likelihood of Tdap vaccination was increased in both the acute COVID epoch [aOR= 2.01; CI 1.74-2.34] and the chronic COVID epoch [aOR = 1.38; CI 1.24-1.54]. The likelihood of Flu vaccination also significantly increased from pre-COVID to acute COVID [aOR=1.25; CI 1.2-1.39].  Notably, Flu vaccination uptake was dramatically reduced from pre-COVID to chronic COVID [aOR=0.67; CI 0.61-0.73].


Conclusion:

Tdap and Flu vaccination rates peaked during acute COVID, likely correlating with amplified health concerns during the pandemic. After acute COVID, vaccination rates were sustained for Tdap, but decreased for Flu. Future studies are needed to elucidate health factors influencing rates of vaccination uptake.