Epidemiology
Poster Session 3
Gabriella Lobitz, MD (she/her/hers)
Resident
Rutgers Robert Wood Johnson Medical School
New Brunswick, NJ, United States
Emily B. Rosenfeld, DO (she/her/hers)
Maternal Fetal Medicine Fellow
Robert Wood Johnson Medical School, Rutgers University
New Brunswick, NJ, United States
Rachel Lee, MS
Rutgers Robert Wood Johnson Medical School
New Brunswick, NJ, United States
Deepika Sagaram, MD
Rutgers Robert Wood Johnson Medical School
New Brunswick, NJ, United States
Cande V. Ananth, MPH, PhD
Professor and Vice Chair for Academic Affairs, Department of Obstetrics, Gynecology, and Reproductive Sciences
Rutgers Robert Wood Johnson Medical School
New Brunswick, NJ, United States
We designed a retrospective cohort study utilizing the Nationwide Readmissions Database (2010-2018) to identify singleton births. ICD-9 and ICD-10 codes were used to identify patients with pre-existing CVD and who experience CVD morbidity within the calendar year of index delivery. Associations between mode of delivery and CVD morbidity were determined from Cox proportional hazards regression models before and after adjusting for potential confounders including hospital bed size, teaching status, patient insurance, and income.
Results: Of the 19,217 patients with prior CVD who underwent delivery, 46% (n = 8,914) underwent a cesarean. Rates of CVD hospitalizations per 100,000 delivery discharges were 9,748 and 9,607 for cesarean and vaginal delivery (adjusted hazard ratio [HR] 0.98, 95% confidence interval [CI] 0.77, 1.11) (Table). The risk for stroke was highest in the first 30 days after the index delivery (adjusted HR 1.81, 95% CI 0.87-3.74) and diminished with increasing latency.
Conclusion: In patients with pre-existing CVD, the mode of delivery was not associated with the risk of CVD-related morbidity in the year following delivery. These findings support the recommendations that the usual obstetrical indications should be used to guide the mode of delivery in persons with pre-existing CVD.