Clinical Obstetrics
Poster Session 1
Sun Min Kim, MD, PhD
Seoul National University College of Medicine
Seoul, Seoul-t'ukpyolsi, Republic of Korea
Byoung Jae Kim, MD
Seoul National University College of Medicine
Seoul, Seoul-t'ukpyolsi, Republic of Korea
Seo Hyun Choi, MD
Seoul National University College of Medicine
Seoul, Seoul-t'ukpyolsi, Republic of Korea
SEO HYUN CHOI, MD
Seoul National University College of Medicine
Seoul, Seoul-t'ukpyolsi, Republic of Korea
Data on singleton pregnancy deliveries between January 2014 and October 2019 were obtained from the Korean Health Insurance Review and Assessment Service database. The index date was defined as 266 days before delivery, and the follow-up end date was 42 days after delivery. Women with diagnostic codes for endometriosis within 3 years of the follow-up end date were classified into the endometriosis group. We compared the clinical characteristics and adverse pregnancy outcomes between women with endometriosis and those without endometriosis.
Results: In total, 1,251,597 pregnant women were enrolled, of which 32,951(2.6%) were assigned to the endometriosis group. The mean maternal age was higher, and the rates of nulliparity and assisted reproductive technology were higher in the endometriosis group than in the non-endometriosis group. Women with endometriosis had significantly higher adverse pregnancy outcomes than those without endometriosis after adjusting for confounding factors. Adverse pregnancy outcomes associated with endometriosis included preterm labor, preterm birth, gestational hypertensive disorders, fetal growth restriction, placenta previa, placental abruption, antepartum and postpartum hemorrhage, and stillbirth. Additionally, cesarean delivery was significantly associated with endometriosis. The cesarean delivery rate was significantly higher in the endometriosis group than in the non-endometriosis group even when excluding cases with antenatal obstetric complications that could increase the risk of cesarean delivery
Conclusion:
Women with endometriosis have a significantly higher risk of adverse pregnancy outcomes even after successful conception.